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Items for "microparticles"

Tissue factor-positive microparticles: Cellular origin and association with coagulation activation in patients with colorectal cancer

The pathogenesis of hypercoagulability in cancer is not entirely understood. We hypothesized that in cancer patients circulating tissue factor-positive microparticles (TF + MPs) are increased and associated with hemostatic system activation...

Keywords: Cancer, microparticles, Tissue factor, hemostasis, platelets

01/2007 | Thrombosis and Haemostasis, Schattauer

New locations of intravascular tissue factor: Indications

Tissue factor (TF) is the major initiator of blood coagulation, and a mediator of inflammation, angiogenesis, and carcinogenesis...

Keywords: Tissue-Faktor, Gewebethromboplastin, Blutgerinnung, Enkryptierung, Aktivierung, Plättchen, Monozyten, Eosinophile, Neutrophile, Mikropartikel, intravasal, Entzündung

01/2007 | Hämostaseologie, Schattauer

Plasma tissue factor antigen in localized prostate cancer: Distribution, clinical significance and correlation with haemostatic activation markers

Tissue factor (TF) is involved in cancer growth and metastasis, and haemostatic abnormalities are found in most patients with advanced malignancies, including prostate cancer (PC)...

Keywords: tissue factor / factor VII, Cancer, microparticles

03/2007 | Thrombosis and Haemostasis, Schattauer

Monocyte IL-10 produced in response to lipopolysaccharide modulates thrombin generation by inhibiting tissue factor expression and release of active tissue factor-bound microparticles

Lipopolysaccharide (LPS)-stimulated monocytes are known to have a procoagulant effect. This property is currently explained by the fact that monocytes, in response to LPS, can express tissue factor (TF) and undergo a process of membrane microvesiculation...

Keywords: interleukin-10, monocytes, thrombin generation, Tissue factor, microparticles