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Items for "Microarrays"

Molecular Diagnosis. Classification, Model Selection and Performance Evaluation

OBJECTIVES: We discuss supervised classification techniques applied to medical diagnosis based on gene expression profiles...

Keywords: Microarrays, statistical classification, generalization error, model assessment, gene selection

01/2005 | Methods of Information in Medicine, Schattauer
Testing Differential Gene Expression in Functional Groups. Goemans Global Test versus an ANCOVA Approach

OBJECTIVES: Single genes are not, in general, the primary focus of gene expression experiments. The researcher might be more interested in relevant pathways, functional sets, or genomic regions consisting of several genes...

Keywords: Microarrays, ANCOVA, global test, permutation test

01/2005 | Methods of Information in Medicine, Schattauer
Application of leukocyte transcriptomes to assess systemic consequences of risk factors for cardiovascular disease

Prevention of cardiovascular disease (CVD) remains a major health issue in the Western world...

Keywords: cardiovascular risk factor, inflammation, Microarrays, monocyte, Phenotype

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter