OBJECTIVES: Microarray gene expression experiments have a complex technical background. Knowledge about certain technical details is inevitable to judge alternatives for both experimental design and analysis...
Keywords: Agilent, chip, comparative hybridization, Gene expression, microarray, technical variance
01/2005 | Methods of Information in Medicine, SchattauerOBJECTIVES: The high density oligonucleotide microarrays from Affymetrix (Affymetrix GeneChips) are very popular in biomedical research...
Keywords: Affymetrix, microarray, normalization, data preprocessing
01/2005 | Methods of Information in Medicine, SchattauerBackground: The development of diagnostic procedures based on microarray analysis confronts the bioinformatician and the biomedical researcher with a variety of challenges...
Keywords: microarray, Gene Analysis Management System (GAMS), bioinformatics
01/2006 | Methods of Information in Medicine, SchattauerThe kinin B2 receptor, which is constitutively expressed in a large number of tissues, mediates most of the known effects of bradykinin (BK)...
Keywords: bradykinin receptor, kidney, knockout mice, microarray
01/2006 | Biological Chemistry, Walter de GruyterTaurine is the most abundant free amino acid in heart muscle and protects against heart failure...
Keywords: compatible organic osmolytes, gene disruption, knockout mice, microarray
10/2006 | Biological Chemistry, Walter de GruyterTraditional gene expression studies typically focus on one or a few genes of interest...
Keywords: cardiovascular diseases, gene expression profile, Heart failure, microarray
05/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterIn the emerging field of
Keywords: allergy, biochip, component resolved diagnosis, IgE, microarray, molecular diagnostics, recombinant allergen
12/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterIn the emerging field of
Keywords: allergy, biochip, component resolved diagnosis, IgE, microarray, molecular diagnostics, recombinant allergen, Allergenchip, Allergie, Komponenten-basierte Diagnose, molekulare Diagnose, microarray, rekombinante Allergene
08/2005 | LaboratoriumsMedizin, Walter de GruyterConsider a probability model Pθ,α, where θ=(θ1,θ2,…,θk)T is a parameter vector of interest, and α is some nuisance parameter...
Keywords: selection of populations, exponential families, Bayes decision rule, Bayes factor, microarray
01/2007 | Statistics & Decisions, Oldenbourg WissenschaftsverlagKeywords: ABCA4 gene, denaturing high performance liquid chromatography (DHPLC), microarray
09/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterDirect detection technologies for pathogenic microorganisms are emerging to be applied in the diagnosis of serious bloodstream infections and infections at sterile body sites, as well as for quality control measures prior to the release of sterile blood products and to ascertain microbial safety of food...
Keywords: bacteraemia, blood culture, flow cytometry, hybridisation, matrix-assisted laser-desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF), microarray, microbial food safety, nucleic acid-based technology (NAT), nucleic acid sequence based amplification (NASBA), PCR, proteomic profiling, sepsis
07/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterKallikrein-related peptidase 3 (KLK3, also known as prostate-specific antigen, PSA) is a chymotrypsin-like kallikrein that has anti-angiogenic properties...
Keywords: Angiogenesis, cell culture, microarray, prostate cancer, PSA
06/2008 | Biological Chemistry, Walter de GruyterPolyamines are essential polycationic molecules involved in multiple cellular events, including cell differentiation, division and death...
Keywords: malaria, microarray, suppression subtractive hybridisation, Transcriptome
02/2008 | Biological Chemistry, Walter de Gruyter