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metalloprotease
Items for "metalloprotease"
Insularinase A, a prothrombin activator from Bothrops insularis venom, is a metalloprotease derived from a gene encoding protease and disintegrin domains
The first low-molecular-mass metalloprotease presenting prothrombin activating activity was purified from
Keywords: Bothrops insularis, Coagulation, endothelial cell, metalloprotease, prothrombin activator, snake venom
06/2005 | Biological Chemistry, Walter de GruyterThe protease domain of procollagen C-proteinase (BMP1) lacks substrate selectivity, which is conferred by non-proteolytic domains
Procollagen C-proteinase (PCP) removes the C-terminal pro-peptides of procollagens and also processes other matrix proteins...
Keywords: astacin, BMP1, CUB-EGF modules, metalloprotease, metzincin, procollagen I
05/2007 | Biological Chemistry, Walter de GruyterTwo α subunits and one β subunit of meprin zinc-endopeptidases are differentially expressed in the zebrafish Danio rerio
Meprins are members of the astacin family of metalloproteases expressed in epithelial tissues, intestinal leukocytes and certain cancer cells...
Keywords: astacin, metalloprotease, metzincin, zebrafish
05/2007 | Biological Chemistry, Walter de GruyterMetastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17
Metalloproteases play a complex role in tumor progression. While the activity of some ADAM, ADAMTS and matrix metalloproteases (MMPs) seems to be protumorigenic, the activity of others seems to prevent tumor progression...
Keywords: extracellular matrix, GPI-anchored, metalloprotease, oncogenesis, proteomics, shedding
08/2008 | Biological Chemistry, Walter de GruyterActivity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP protease
Human growth and development are conditioned by insulin-like growth factors (IGFs), which have also implications in pathology...
Keywords: adamalysin, ADAMs, astacin, IGF, IGFBP protease, metalloprotease, metzincin, pappalysin
11/2007 | Biological Chemistry, Walter de GruyterCloning, expression and characterization of insulin-degrading enzyme from tomato (Solanum lycopersicum )
A cDNA encoding insulin-degrading enzyme (IDE) was cloned from tomato (
Keywords: insulinase, insulysin, metalloprotease, plant, proteolysis
01/2008 | Biological Chemistry, Walter de Gruyter