Items for "metabolite interference"

Evaluation of a novel semi-automated HPLC procedure for whole blood cyclosporin A confirms equivalence to adjusted monoclonal values from Abbott TDx

The problem in the measurement of cyclosporin (CyA) is that the widely used immuno-based assays suffer from interference by metabolites present in unpredictable excess...

Keywords: Abbott, cyclosporin, HPLC, liquid chromatography-mass spectrometry (LC-MS), metabolite interference, monoclonal, polyclonal