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Items for "mesangial cells"

Nitric oxide modulates expression of extracellular matrix genes linked to fibrosis in kidney mesangial cells

Mesangial cells are thought to be important mediators of glomerular inflammation and fibrosis...

Keywords: connective tissue growth factor (CTGF), extracellular matrix, mesangial cells, nitric oxide, representational difference analysis (RDA), transcriptional regulation

05/2007 | Biological Chemistry, Walter de Gruyter
Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner

Sphingosine kinases (SKs) are key enzymes regulating the production of sphingosine-1-phosphate (S1P), which determines important cell responses including cell growth and death...

Keywords: Apoptosis, ceramide, mesangial cells, sphingosine-1-phosphate, sphingosine kinase knockout mice

11/2008 | Biological Chemistry, Walter de Gruyter