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Items for "melting curve analysis (MCA)"

Screening for genetic heterogeneity in the interferon sensitivity determining region of the hepatitis C virus genome by polymerase chain reaction with melting curve analysis

Background: Although mutations in the interferon (IFN) sensitivity determining region (ISDR) of hepatitis C virus (HCV) have been reported to be useful as a predictive viral factor for IFN therapy in patients infected with HCV-1b, such laboratory research has not been favorably translated into the clinic...

Keywords: hepatitis C virus (HCV), interferon (IFN), interferon sensitivity determining region (ISDR), melting curve analysis (MCA), quasispecies

07/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter