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Items for "melanoma"
The ability of different forms of heparins to suppress P-selectin function in vitro correlates to their inhibitory capacity on bloodborne metastasis in vivo
Ample evidence suggests that many of the in vivo anti-metastatic effects by heparins reflect their actions on P-selectin-mediated binding...
Keywords: anticoagulants, heparin, P-selectin, neoplasm metastasis, melanoma
03/2006 | Thrombosis and Haemostasis, SchattauerCysteine cathepsins in human cancer
Proteases play causal roles in the malignant progression of human tumors. This review centers on the roles in this process of cysteine cathepsins, i.e., peptidases belonging to the papain family (C1) of the CA clan of cysteine proteases...
Keywords: breast carcinoma, cathepsin B, colorectal carcinoma, cystatins, cysteine cathepsins, glioblastoma, melanoma, prostate carcinoma
11/2004 | Biological Chemistry, Walter de GruyterDetailed analysis of MIA protein by mutagenesis
MIA (melanoma inhibitory activity) has been identified as a small protein secreted by malignant melanoma cells that interacts with extracellular matrix proteins including fibronectin...
Keywords: melanoma, melanoma inhibitory activity, MIA function, mutagenesis
12/2006 | Biological Chemistry, Walter de Gruyter