OBJECTIVES: In this paper, we quantify the fractal scaling characteristics of phrenic neurograms during eupnea in piglets, the output of the respiratory neural network that accompany maturation We also attempt to investigate whether the fractal properties are altered with maturation. METHODS: The phrenic neurogram in piglets was recorded from the C5 phrenic nerve during eupnea at four postnatal ages; the 3-6 days, the 7-14 days, 15-21 days and the 26-31 days age groups and analyzed using the maximum likelihood estimator (MLE). RESULTS: Our results suggest that the mean fractal measures over a recording of five consecutive breaths during eupnea for each piglet in each group were higher during the first 6 days and slightly decreased for the 7-14 days and significantly decreased for the 15-21 days and significantly increased for subsequent maturation (the 26-31 days old group). CONCLUSIONS: We suggest that there is a significant alteration in the fractal organization in piglet respiratory patterns during maturation and a decrease in the fractal value is unique to the 15-21 days old group.
Keywords: Fractals, maturation, phrenic neurograms, eupnea
01/2004 | Methods of Information in Medicine, SchattauerFree propeptides are known to function as inhibitors of the parental mature cysteine cathepsins...
Keywords: aminopeptidase, cysteine peptidase, inhibition, maturation, mini-chain
09/2005 | Biological Chemistry, Walter de GruyterSyncytin-1, the envelope protein of ERVWE1, an endogenous retrovirus of the HERV-W family, plays an important role in regulating fusion of the placental trophoblast...
Keywords: cell-cell fusion, cytoplasmic domain, HERV-W, maturation, surface expression
08/2006 | Biological Chemistry, Walter de GruyterSeveral studies have proposed that angiotensin II (Ang II) binds to its receptor AT1 through interactions with residues in helices V and VI, suggesting that the distance between these helices is crucial for ligand binding...
Keywords: dimerization, folding, GPCR, maturation, site-directed mutagenesis
03/2006 | Biological Chemistry, Walter de GruyterKeywords: autonomic nervous system, baroreceptor reflex, Heart rate variability, maturation, premature, respiratory modulation
08/2006 | Journal of Perinatal Medicine, Walter de GruyterThe 26S proteasome is the key eukaryotic protease responsible for the degradation of intracellular proteins...
Keywords: assembly factor, maturation, protein complex, yeast
09/2008 | Biological Chemistry, Walter de Gruyter