Items for "mast cell degranulation"

Direct thrombin inhibitors built on the azaphenylalanine scaffold provoke degranulation of mast cells

The main structural feature of direct thrombin inhibitor LK-732 responsible for the appropriate interaction at the thrombin active site is a strong basic group...

Keywords: Thrombin inhibitors, azaphenylalanine scaffold, mast cell degranulation, basicity, rat