Items for "liver resection"
Background: The increase in plasma aspartate (AST) and alanine (ALT) aminotransferase after liver resection is multifactorial, and a major problem is the difficult quantification of the impact of each factor involved.
Methods: Regression analysis of a large series of measurements for 92 hepatectomy patients was carried out to assess in detail the postoperative evolution of AST and ALT, together with related components.
Results: The best correlate of increased AST and ALT on postoperative day 1 was the duration of surgery (T-surg) (r2=0.31 and 0.29), with a lower correlation for intraoperative liver ischemia (T-isch) (r2=0.22 and 0.17, respectively; p<0.001 for all)...
Keywords: alanine aminotransferase, aspartate aminotransferase, bilirubin, liver ischemia, liver resection
03/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Background: The aim of this study was to provide an improved outline of the patterns and correlates of changes in plasma bilirubin after partial hepatectomy.
Methods: A large series of blood measurements and complementary variables were prospectively collected from 85 patients undergoing liver resection, and bilirubin correlations were assessed by regression analysis.
Results: Early postoperatively, the best simultaneous correlates of increasing bilirubin were the preoperative value, the duration of surgery, and the number of blood transfusions (r2=0.74, p<0.001)...
Keywords: liver dysfunction, liver ischemia, liver resection, plasma bilirubin, sepsis
11/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter