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Items for "liquid chromatography-tandem mass spectrometry"

Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry

In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard...

Keywords: cyclosporin A, cyclosporin D, liquid chromatography-tandem mass spectrometry, specificity

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Quantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry

A convenient liquid chromatography-tandem mass spectrometry method for the quantification of the triazole antifungal agent voriconazole in plasma samples is described...

Keywords: liquid chromatography-tandem mass spectrometry, Solid phase extraction, therapeutic drug monitoring, voriconazole

07/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Release of anandamide from blood cells

Background: Endogenous ligands of cannabinoid receptors (endocannabinoids), in particular anandamide (arachidonylethanolamide), have been recognized as being of crucial importance in a variety of physiological functions...

Keywords: anandamide (arachidonylethanolamide), liquid chromatography-tandem mass spectrometry, preanalytical period

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Predicted influence of sample hematocrit on injected mass of internal standard in mass spectrometry assays utilizing simple protein precipitation for sample preparation

Background: The injected mass of internal standard is often monitored in mass spectrometry assays to flag aberrant specimen processing...

Keywords: hematocrit, internal standard, liquid chromatography-tandem mass spectrometry, Quality Control