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Items for "lipoprotein"

Paraoxonase and platelet-activating factor acetylhydrolase activities in lipoproteins of ?-thalassemia/hemoglobin E patients

Background: Iron-induced oxidative stress may be implicated in the alteration of the lipoprotein-associated antioxidant enzymes paraoxonase 1 (PON1) and platelet-activating factor acetylhydrolase (PAF-AH), leading to atherosclerosis-related vascular complication in patients with ?-thalassemia hemoglobin E (?-thal/Hb E).

Methods: Plasma and lipoprotein enzyme activities of PON1 and PAF-AH were studied in 13 mild to moderate and 15 severe cases of ?-thal/Hb E in comparison with 15 normal subjects.

Results: PON1 activity was significantly reduced in association with oxidative stress in the patients...

Keywords: lipoprotein, oxidative stress, paraoxonase, platelet-activating factor acetylhydrolase, ?-thalassemia

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Conjugated linoleic acid suppresses the secretion of atherogenic lipoproteins from human HepG2 liver cells

Studies in healthy humans have shown that consumption of conjugated linoleic acid (CLA) significantly reduced very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) blood concentrations...

Keywords: apolipoprotein B100 (apoB100), atherosclerosis, cholesterol, conjugated linoleic acid, HepG2 liver cells, lipoprotein

03/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter