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Items for "knockout mice"

Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genes

The kinin B2 receptor, which is constitutively expressed in a large number of tissues, mediates most of the known effects of bradykinin (BK)...

Keywords: bradykinin receptor, kidney, knockout mice, microarray

01/2006 | Biological Chemistry, Walter de Gruyter
Switch from actin ?1 to ?2 expression and upregulation of biomarkers for pressure overload and cardiac hypertrophy in taurine-deficient mouse heart

Taurine is the most abundant free amino acid in heart muscle and protects against heart failure...

Keywords: compatible organic osmolytes, gene disruption, knockout mice, microarray

10/2006 | Biological Chemistry, Walter de Gruyter