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Items for "kininogen"

A possible alternative mechanism of kinin generation in vivo by cathepsin L

We investigated the ability of cathepsin L to induce a hypotensive effect after intravenous injection in rats and correlated this decrease in blood pressure with kinin generation...

Keywords: blood pressure decrease, bradykinin, cathepsins, inflammation, kinin, kininogen

07/2005 | Biological Chemistry, Walter de Gruyter
Genetically altered animal models in the kallikrein-kinin system

Transgenic and gene-targeting technologies allowing the generation of genetically altered animal models have greatly advanced our understanding of the function of specific genes...

Keywords: bradykinin, kininase, kininogen, kinin receptor, knockout animals, Transgenic animals

02/2006 | Biological Chemistry, Walter de Gruyter
A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

The human kallikrein locus on chromosome 19q13.3–13.4 contains kallikrein 1 – the tissue kallikrein – and 14 related serine proteases...

Keywords: Cancer, evolution, hormone, inflammation, kininogen

06/2006 | Biological Chemistry, Walter de Gruyter