We investigated the ability of cathepsin L to induce a hypotensive effect after intravenous injection in rats and correlated this decrease in blood pressure with kinin generation...
Keywords: blood pressure decrease, bradykinin, cathepsins, inflammation, kinin, kininogen
07/2005 | Biological Chemistry, Walter de GruyterTransgenic and gene-targeting technologies allowing the generation of genetically altered animal models have greatly advanced our understanding of the function of specific genes...
Keywords: bradykinin, kininase, kininogen, kinin receptor, knockout animals, Transgenic animals
02/2006 | Biological Chemistry, Walter de GruyterThe human kallikrein locus on chromosome 19q13.3–13.4 contains kallikrein 1 – the tissue kallikrein – and 14 related serine proteases...
Keywords: Cancer, evolution, hormone, inflammation, kininogen
06/2006 | Biological Chemistry, Walter de Gruyter