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Items for "kinin"

Inhibition of sequestration of human B2 bradykinin receptor by phenylarsine oxide or sucrose allows determination of a receptor affinity shift and ligand dissociation in intact cells

Depending on their interaction with intracellular proteins, G protein-coupled receptors (GPCR) often display different affinities for agonists at 37°C...

Keywords: G protein-coupled receptor, internalization, kinin, NPXXY

09/2004 | Biological Chemistry, Walter de Gruyter
A possible alternative mechanism of kinin generation in vivo by cathepsin L

We investigated the ability of cathepsin L to induce a hypotensive effect after intravenous injection in rats and correlated this decrease in blood pressure with kinin generation...

Keywords: blood pressure decrease, bradykinin, cathepsins, inflammation, kinin, kininogen

07/2005 | Biological Chemistry, Walter de Gruyter