SearchPublisher and Institutes
You are here: Home :: Keyword index :: hyd bis kel :: kallikrein - kelp 
kallikrein
Items for "kallikrein"
Plasma prekallikrein/kallikrein processing by lysosomal cysteine proteases
Plasma kallikrein plays a role in coagulation, fibrinolysis and inflammation. Cathepsins B and L participate in (patho)physiological processes such as peptide antigen processing, tissue remodeling events, protein turnover in cells, hormone processing and tumor invasion...
Keywords: cathepsins, kallikrein, kinin system, proteolysis
11/2004 | Biological Chemistry, Walter de GruyterEnzymatic profiling of human kallikrein 14 using phage-display substrate technology
The human
Keywords: extracellular matrix protein, kallikrein, phage display, protease, substrate
03/2005 | Biological Chemistry, Walter de GruyterRecombinant kallikrein expression: site-specific integration for hK6 production in human cells
Kallikreins have been implicated in carcinogenesis and are promising biomarkers for the diagnosis and follow-up of various cancers...
Keywords: bioreactor, human cells, kallikrein, recombinant proteins, targeted integration of transgene
06/2006 | Biological Chemistry, Walter de GruyterIncrease in kinins on post-exercise hypotension in normotensive and hypertensive volunteers
Post-exercise hypotension is an important event for blood pressure regulation, especially in hypertensive individuals...
Keywords: aerobic exercise, circuit weight training, hypertension, kallikrein, kinins
05/2007 | Biological Chemistry, Walter de GruyterDevelopment of peptides specifically modulating the activity of KLK2 and KLK3
The prostate produces several proteases, the most abundant ones being kallikrein-related peptidase 3 (KLK3, PSA) and KLK2 (hK2), which are potential targets for tumor imaging and treatment...
Keywords: hK2, kallikrein, peptide modification, phage display, prostate cancer, PSA
06/2008 | Biological Chemistry, Walter de GruyterKallikreins as microRNA targets: an in silico and experimental-based analysis
microRNAs (miRNAs) are non-coding RNAs that target specific mRNAs. They have been shown to control many biological processes including cancer pathogenesis...
Keywords: Cancer, kallikrein, KLK, microRNA, miRNA, RNAi, siRNA, tumor markers
06/2008 | Biological Chemistry, Walter de GruyterKallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration
Tissue kallikrein KLK1 and the kallikrein-related peptidases KLK2–15 are a subfamily of serine proteases that have defined or proposed roles in a range of central nervous system (CNS) and non-CNS pathologies...
Keywords: axon injury, kallikrein, Prognosis, serine protease
06/2008 | Biological Chemistry, Walter de GruyterDevelopment of diabetic cardiomyopathy and the kallikrein-kinin system – new insights from B1 and B2 receptor signaling
Diabetic cardiomyopathy is a specific cardiomyopathy which develops in patients with diabetes mellitus in the absence of coronary atherosclerosis and hypertension...
Keywords: B1 receptor, cardiac inflammation, diabetic cardiomyopathy, kallikrein
06/2008 | Biological Chemistry, Walter de GruyterFunctions of KLK4 and MMP-20 in dental enamel formation
Two proteases are secreted into the enamel matrix of developing teeth. The early protease is enamelysin (MMP-20)...
Keywords: amelogenesis imperfecta, EMSP1, enamelysin, kallikrein, Matrix metalloproteinase, tooth enamel
06/2008 | Biological Chemistry, Walter de GruytermicroRNAs: a new frontier in kallikrein research
microRNAs (miRNAs) are a recently discovered class of small non-coding RNAs that regulate gene expression...
Keywords: bioinformatics, kallikrein, KLK, microRNA, RNAi, target validation
06/2008 | Biological Chemistry, Walter de GruyterBauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties
Plant proteinase inhibitors are involved in the regulation of the activity of many proteinases and, in consequence, in biological processes driven by proteolysis...
Keywords: cathepsin, inflammation, kallikrein, Kunitz, plant proteinase inhibitors, trypsin
08/2008 | Biological Chemistry, Walter de GruyterTissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7 , and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function
Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family...
Keywords: kallikrein, mRNA splicing, pancreas, promoter analysis, tissue specific, Transcription factors
02/2008 | Biological Chemistry, Walter de Gruyter