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Items for "intravital fluorescence microscopy"

Antithrombin is as effective as heparin and hirudin to prevent formation of microvascular thrombosis in a murine model

A recently published post-hoc analysis of a trial using high-dose antithrombin (AT) in septic patients (KyberSept) revealed significant reduction of lethality when no concomitant heparin was administered, whereas patients with the combination of heparin and AT did not benefit in terms of survival...

Keywords: intravital fluorescence microscopy, hairless mouse, ear model, light/dye injury, occlusion rate

09/2006 | Thrombosis and Haemostasis, Schattauer
Fibronectin binding proteins contribute to the adherence of Staphylococcus aureus to intact endothelium in vivo

Staphylococcal adhesins mediate attachment to matrix proteins and endothelial cells in vitro, yet, their role in primary adherence to the physiologic vessel wall has not been studied in vivo, and complex endocarditis models yielded ambiguous results...

Keywords: Staphylococcus aureus, endothelium, intravital fluorescence microscopy, fibronectin binding protein A, adherence

08/2006 | Thrombosis and Haemostasis, Schattauer