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Items for "interleukin-10"

Interleukin-10 promoter polymorphism and venous thrombosis: A case-control study

The human interleukin-10 promoter gene is highly polymorphic. IL-10 polymorphisms have been associated with various autoimmune and lymphoproliferative disorders...

Keywords: deep vein thrombosis, interleukin-10, factor V Leiden, hereditary thrombosis risk factor

07/2006 | Thrombosis and Haemostasis, Schattauer
Monocyte IL-10 produced in response to lipopolysaccharide modulates thrombin generation by inhibiting tissue factor expression and release of active tissue factor-bound microparticles

Lipopolysaccharide (LPS)-stimulated monocytes are known to have a procoagulant effect. This property is currently explained by the fact that monocytes, in response to LPS, can express tissue factor (TF) and undergo a process of membrane microvesiculation...

Keywords: interleukin-10, monocytes, thrombin generation, Tissue factor, microparticles

04/2007 | Thrombosis and Haemostasis, Schattauer
High-sensitivity C-reactive protein concentration in patients with myocardial infarction-environmental factors, and polymorphisms in interleukin-10 and CD14 genes

Background: It has been shown that high-sensitivity C-reactive protein (hsCRP) concentrations are associated with elevated risk of myocardial infarction, but the mechanisms regulating hsCRP concentration are not completely elucidated yet...

Keywords: atherosclerosis, CD14, environmental factors, genetic polymorphisms, interleukin-10, myocardial infarction

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter