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Items for "interference"

Gammopathy interference in clinical chemistry assays: mechanisms, detection and prevention

Monoclonal gammopathy is characterized by the presence of an M-protein in serum or urine that has homogeneous structural and functional properties...

Keywords: gammopathy, interference, paraprotein, M-protein

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
IFCC Guideline for sampling, measuring and reporting ionized magnesium in plasma

Analyzers with ion-selective electrodes (ISEs) for ionized magnesium (iMg) should yield comparable and unbiased results for iMg...

Keywords: erythrocyte effect, heparin, influence factors, interference, ionized calcium, ionized magnesium, ion-selective electrode, lipophilic anions, liquid junction potential, pH, protein, sampling, silicone, sodium

00/0000 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Interference in a homogeneous assay for low-density lipoprotein cholesterol by lipoprotein X

Background: Homogeneous assays for cholesterol in low-density lipoprotein (LDL) are currently in wide use for guideline-based diagnosis and monitoring of dyslipaemic or coronary conditions...

Keywords: interference, lipoprotein X, low-density lipoprotein cholesterol, negative bias, ultracentrifugation

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
On detecting interference from endogenous antibodies in immunoassays by doubling dilutions test

The clinical laboratory may perform additional test or tests to ascertain the integrity of immunoassay analyses when the results are in doubt...

Keywords: analytical inaccuracy, doubling dilutions test, immunoassay, interference

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Guidelines for sampling, measuring and reporting ionized magnesium in undiluted serum, plasma or blood: International Federation of Clinical Chemistry and Laboratory Medicine (IFCC): IFCC Scientific Division, Committee on Point of Care Testing

All analyzers with ion-selective electrodes for ionized magnesium (iMg) should yield comparable and unbiased results...

Keywords: erythrocyte, heparin, influence factors, interference, ionized calcium, ionized magnesium, ion-selective electrode, lipophilic anions, liquid junction potential, pH, protein, sampling, silicone, sodium

05/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Interferences in coagulation tests – evaluation of the 570-nm method on the Dade Behring BCS analyser

The Dade Behring BCS is a coagulation analyser with optical reaction detection (standard 405 nm)...

Keywords: coagulation analyser, interference, method evaluation, optical detection

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Vitamin C and aberrant electrolyte results

Vitamin C interferes with assays involving the redox-reaction. However, the interference of Vitamin C with electrolytes has not been reported...

Keywords: Beckman Synchron LX20, electrolytes, interference, vitamin C

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Evaluation of the Konelab 20XT clinical chemistry analyzer

The Konelab 20XT (Thermo Electron Oy, Finland) is a clinical chemistry analyzer for colorimetric, immunoturbidimetric and ion-selective electrode measurements...

Keywords: Evaluation, imprecision, inaccuracy, instrument comparison, interference

06/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Utilizing ultrafiltration to remove alkaline phosphatase from clinical analyzer water

Alkaline phosphatase (ALP) conjugated to antibodies is often used in enzyme immunoassays (EIAs)...

Keywords: alkaline phosphatase, Bacteria, interference, Ultrafiltration, Water

05/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Strong interference of hemoglobin concentration on CSF total protein measurement using the trichloroacetic acid precipitation method

Background: Among other methods, trichloroacetic acid precipitation is used to quantify total protein in cerebrospinal fluid (CSF).

Methods: We analyzed the influence of hemoglobin on total protein concentration assayed by the trichloroacetic acid method and compared the results to the benzethonium chloride method.

Results: Four CSF samples were spiked with different amounts of hemoglobin, leading to overestimation of protein concentration when assayed by the trichloroacetic acid method...

Keywords: cerebrospinal fluid, hemoglobin, interference, protein, trichloroacetic acid

01/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter