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insulin secretion
Items for "insulin secretion"
Isolation and structural characterisation of a novel 13-amino acid insulin-releasing peptide from the skin secretion of Agalychnis calcarifer
We describe the isolation and characterisation of an insulinotropic peptide from the skin secretions of
Keywords: Agalychnis calcarifer, amphibian peptides, insulin secretion, insulinotropic peptide, RK-13
06/2005 | Biological Chemistry, Walter de GruyterAntidiabetic potential of two novel fatty acid derivatised, N-terminally modified analogues of glucose-dependent insulinotropic polypeptide (GIP): N -AcGIP(LysPAL16) and N -AcGIP(LysPAL37)
Fatty acid derivatisation was used to develop two novel, long-acting, N-terminally modified, glucose-dependent insulinotropic polypeptide (GIP) analogues,
Keywords: dipeptidylpeptidase IV (DPP IV), fatty acid derivatisation, GIP analogues, glucose-dependent insulinotropic polypeptide (GIP), insulin secretion, obese diabetic ob/ob mice
07/2005 | Biological Chemistry, Walter de GruyterCharacterisation and glucoregulatory actions of a novel acylated form of the (Pro3)GIP receptor antagonist in type 2 diabetes
In this study, we tested the biological activity of a novel acylated form of (Pro3)glucose-dependent insulinotropic polypetide [(Pro3)GIP] prepared by conjugating palmitic acid to Lys16 to enhance its efficacy
Keywords: antihyperglycaemic activity, DPP IV, fatty acid-linked peptides, GIP receptor antagonists, insulin secretion, obese diabetic (ob/ob) mice
02/2007 | Biological Chemistry, Walter de GruyterMetabolic effects of sub-chronic ablation of the incretin receptors by daily administration of (Pro3)GIP and exendin(9–39)amide in obese diabetic (ob/ob ) mice
Effects of chemical ablation of the GIP and GLP-1 receptors on metabolic aspects of obesity-diabetes were investigated using the stable receptor antagonists (Pro3)GIP and exendin(9–39)amide...
Keywords: antagonism, exendin(9?39)amide, glucose homeostasis, insulin secretion, ob/ob mice, (Pro3)GIP
02/2007 | Biological Chemistry, Walter de Gruyter