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Items for "insulin resistance"

Increased cardiovascular risk markers in obesity are associated with body adiposity: Role of leptin

Epidemiological studies have shown that obesity is associated with increased blood concentrations of proinflammatory factors and markers of endothelial dysfunction such as fibrinogen, C-reactive protein (CRP), and vonWillebrand factor (vWF)...

Keywords: obesity, adipose tissue, inflammation, leptin, insulin resistance

06/2006 | Thrombosis and Haemostasis, Schattauer
Evaluation of genetic predisposition to insulin resistance by nutrient-induced insulin output ratio (NIOR)

Background: New tools to identify genotype-phenotype interactions need to be described and implemented...

Keywords: gene polymorphisms, individualized nutrition, insulin resistance, metabolic syndrome, obesity, prognostic marker

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-&ggr;2 (PPAR&ggr;-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population

Background: The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-&ggr;2 (PPAR&ggr;-2) gene has been variably associated with insulin resistance, obesity and type 2 diabetes in several populations...

Keywords: insulin resistance, Iranian population, obesity, peroxisome proliferator-activated receptor-2 (PPAR-2), Pro12Ala, type 2 diabetes

04/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Insulin resistance and enhanced protein glycation in men with prehypertension

Background: Insulin resistance and hyperinsulinemia have been reported among patients with hypertension...

Keywords: hyperinsulinemia, hypertension, insulin resistance, prehypertension, protein glycation

12/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Association of high-sensitive C-reactive protein with advanced stage ?-cell dysfunction and insulin resistance in patients with type 2 diabetes mellitus

Background: Type 2 diabetes mellitus is associated with increased cardiovascular risk...

Keywords: high-sensitivity C-reactive protein (hsCRP), homeostatic model assessment (HOMA), insulin resistance, intact proinsulin, type 2 diabetes

05/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Surrogate markers of insulin resistance in assessing individuals with new categories “prehypertension” and “prediabetes”

Background: There are few data on the impact of insulin resistance on the recently defined categories of prehypertension (PHT) and prediabetes (PDM)...

Keywords: insulin resistance, metabolic syndrome, prediabetes, prehypertension, 75-g oral glucose tolerance test

01/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Comparability of indices for insulin resistance and insulin secretion determined during oral glucose tolerance tests

Background: Impaired insulin secretion (IS) and insulin resistance (IR) play an essential role in the pathogenesis of type 2 diabetes mellitus...

Keywords: glucose tolerance test, insulin indices, insulin resistance, insulin sensitivity, type 2 diabetes

07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Interleukin-6 gene promoter –174G/C polymorphism and insulin resistance: a pilot study

Background: The aim of this pilot study was to evaluate the relationship between interleukin-6 promoter –174G/C (IL-6 –174G/C) polymorphism and insulin resistance (IR) in obese patients with coronary heart disease (CHD).

Methods: Twenty obese male patients with CHD were selected from a larger database of patients (n=606)...

Keywords: adiposity, coronary heart disease, genotype, high-density lipoprotein cholesterol, insulin resistance, Interleukin-6

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter