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Items for "immunoassays"

Magnetorelaxometry of Magnetic Nanoparticles for the Quantitative and Specific Analysis of Biomolecules

The magnetorelaxometry (MRX) is a very promising tool for the realization of a so-called magnetic relaxation immunoassay (MARIA)...

Keywords: magnetorelaxometry, immunoassays, superparamagnetic nanoparticles, fluxgate magnetometers

04/2006 | tm – Technisches Messen, Oldenbourg Wissenschaftsverlag

Diagnostic accuracy of the FIDIS multiplex fluorescent microsphere immunodetection system for anti-extractable nuclear antigen (ENA) antibodies in connective tissue diseases

Background: Anti-extractable nuclear antigen antibodies (ENA) are markers of connective tissue diseases (CTDs).

Methods: We compared FIDIS reagents in the multiplex fluorescent microsphere immunodetection system to INNO-LIA and immunodiffusion for 174 antinuclear antibody-positive patients, 102 with well-defined CTDs and 72 disease controls.

Results: No significant differences were found in sensitivity or specificity between FIDIS and immunodiffusion, or between FIDIS and INNO-LIA for all anti-ENA in all CTD patients; nor were any differences found for individual anti-ENAs within distinct CTDs...

Keywords: anti-extractable nuclear antigen antibodies, antinuclear antibodies, autoimmunity, connective tissue diseases, immunoassays, Luminex, multiplex

04/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Evaluation of immunoassays for the measurement of insulin-like growth factor-I and procollagen type III peptide, indirect biomarkers of recombinant human growth hormone misuse in sport

Insulin-like growth factor-I (IGF-I) and procollagen type III peptide (P-III-P) have been proposed as indirect biomarkers for the detection of the misuse of recombinant human growth hormone in sport...

Keywords: growth hormone, immunoassays, insulin-like growth factor-I (IGF-I), procollagen type III peptide (P-III-P), recombinant human growth hormone (rhGH) biomarkers, Validation

01/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Opinion Paper: The double whammy of endogenous insulin antibodies in non-diabetic subjects

The presence of high affinity/avidity endogenous insulin antibodies in significant amounts in non-diabetic individuals could uniquely be a double whammy...

Keywords: analytical interference, autoimmune hypoglycaemia, hypoglycaemia, immunoassays, insulin antibodies, insulin autoimmune syndrome