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Items for "immune activation"

St. John's wort (Hypericum perforatum) counteracts cytokine-induced tryptophan catabolism in vitro

St. John's wort (Hypericum perforatum) is an ancient folk remedy that has antiviral and antibacterial properties...

Keywords: Hypericum perforatum, immune activation, indoleamine (2,3)-dioxygenase, neopterin, tryptophan

12/2004 | Biological Chemistry, Walter de Gruyter

Inverse association between serum selenium concentrations and parameters of immune activation in patients with cardiac disorders

Background: As a component of the enzyme glutathione peroxidase, the essential trace element selenium contributes to the reduction of peroxides...

Keywords: cardiac disorders, immune activation, neopterin, oxidative stress, selenium, tryptophan degradation

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Anti-inflammatory compound resveratrol suppresses homocysteine formation in stimulated human peripheral blood mononuclear cells in vitro

Inflammation, immune activation and oxidative stress play a major role in the pathogenesis of cardiovascular disorders...

Keywords: homocysteine, immune activation, peripheral blood mononuclear cells (PBMC), resveratrol

10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

The molecular basis of homocysteine thiolactone-mediated vascular disease

Accumulating evidence suggests that a metabolite of homocysteine (Hcy), the thioester Hcy-thiolactone, plays an important role in atherogenesis and thrombosis...

Keywords: atherosclerosis, autoantibodies, cystathionine ?-synthase (CBS), dietary hyperhomocysteinemia, fibrinogen, genetic hyperhomocysteinemia, homocysteine thiolactone hypothesis, immune activation, methylenetetrahydrofolate reductase (MTHFR), protein N-homocysteinylation, thrombosis