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hyperhomocysteinemia
Items for "hyperhomocysteinemia"
Reduced adenosine receptor stimulation as a pathogenic factor in hyperhomocysteinemia
In this review we discuss the hypothesis, and current evidence, that a decreased concentration of the endogenous purine-nucleoside adenosine contributes to the increased cardiovascular risk of patients with hyperhomocysteinemia...
Keywords: Adenosine, cardiovascular disease, dipyridamole, hyperhomocysteinemia
10/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterEffects of homocysteine on vascular and tissue adenosine: a stake in homocysteine pathogenicity?
Homocysteine may have deleterious effects on the cardiovascular system. It has been hypothesized that these effects may be brought about by a decrease in the adenosine concentration via the S-adenosylhomocysteine hydrolase reaction...
Keywords: S-adenosylhomocysteine hydrolase, blood flow, homocysteine pathogenicity, hyperhomocysteinemia
10/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterHyperhomocysteinemia and macromolecule modifications in uremic patients
Hyperhomocysteinemia is present in the majority of well-nourished chronic renal failure and uremic patients...
Keywords: DNA methylation, hyperhomocysteinemia, isopeptide bonds, uremia
10/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterMolecular targeting by homocysteine: a mechanism for vascular pathogenesis
Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Although there is a growing body of evidence that homocysteine plays a causal role in atherogenesis, specific mechanisms to explain the underlying pathology have remained elusive...
Keywords: Albumin, atherogenesis, disulfide bond, glutathione peroxidase, homocysteine, hyperhomocysteinemia, molecular targeting, pKa, sulfhydryl group, vascular pathogenesis
10/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterAsymmetric dimethylarginine, homocysteine and renal function – is there a relation?
The adverse effect of hyperhomocysteinemia on the vascular wall can be partially explained by increasing plasma concentration of asymmetric dimethylarginine (ADMA), a potent inhibitor of nitric oxide synthase...
Keywords: asymmetric dimethylarginine, Hemodialysis, homocysteine, hyperhomocysteinemia
10/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterIncreased homocysteine in heart failure: a result of renal impairment?
Keywords: Heart failure, hyperhomocysteinemia, renal function
11/2006 | Clinical Chemical Laboratory Medicine, Walter de GruyterPlasma homocysteine cutoff values for venous thrombosis
Keywords: cutoff values, hyperhomocysteinemia, Venous thrombosis
02/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterHyperhomocysteinemia and high-density lipoprotein metabolism in cardiovascular disease
Hyperhomocysteinemia (HHcy) is a significant and independent risk factor for cardiovascular disease (CVD) and the underlying mechanism is unclear...
Keywords: atherosclerotic cardiovascular disease, high-density lipoprotein metabolism, hyperhomocysteinemia
12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter