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Items for "hypercholesterolemia"

Polymorphisms in the P-selectin (CD62P) and P-selectin glycoprotein ligand-1 (PSGL-1) genes and coronary heart disease

P-selectin and its ligand, PSGL-1, are cell adhesion molecules that facilitate interaction of platelets, leukocytes and endothelial cells...

Keywords: allele-specific PCR, coronary heart disease, exon re-sequencing, hypercholesterolemia, single nucleotide polymorphisms

09/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
APOA1 polymorphisms are associated with variations in serum triglyceride concentrations in hypercholesterolemic individuals

Background: Apolipoprotein A-I gene (APOA1) polymorphisms have been associated with variations in serum low-density lipoprotein (LDL)- and high-density lipoprotein (HDL)-cholesterol...

Keywords: apolipoprotein A-I, atorvastatin, gene polymorphism, hypercholesterolemia, triglyceride

12/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Inhibition of the ubiquitin-proteasome system: a new avenue for atherosclerosis

Background: The ubiquitin-proteasome system (UPS) is thought to be functionally active in atherosclerosis (AS) lesions...

Keywords: Aspirin, atherosclerosis, hypercholesterolemia, ubiquitin-proteasome system

10/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter