For the first time we have extracted, solubilized and identified growth factors, such as insulin growth factor II (IGF-II), bone morphogenetic protein-2 (BMP-2), and transforming growth factor-? (TGF-?), from archaeological compact human bone and tooth dentin dating from the late pre-ceramic pottery Neolithic (late PPNB) and the early Middle Ages...
Keywords: ancient bone and teeth, bone morphogenetic protein-2 (BMP-2), 2-D electrophoresis, human evolution, insulin growth factor II (IGF-II), transforming growth factor-? (TGF-?)
08/2005 | Biological Chemistry, Walter de Gruyter