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Items for "Hsp70"

Novel insights into the mechanism of chaperone-assisted protein disaggregation

Cell survival under severe thermal stress requires the activity of a bi-chaperone system, consisting of the ring-forming AAA+ chaperone ClpB (Hsp104) and the DnaK (Hsp70) chaperone system, which acts to solubilize and reactivate aggregated proteins...

Keywords: AAA+ protein, chaperone, ClpB, DnaK, Hsp104, Hsp70, protein disaggregation

08/2005 | Biological Chemistry, Walter de Gruyter
Fes1p acts as a nucleotide exchange factor for the ribosome-associated molecular chaperone Ssb1p

The HspBP1 homolog Fes1p was recently identified as a nucleotide exchange factor (NEF) of Ssa1p, a canonical Hsp70 molecular chaperone in the cytosol of Saccharomyces cerevisiae...

Keywords: Fes1p, Hsp70, molecular chaperone, nucleotide exchange factor, yeast

12/2006 | Biological Chemistry, Walter de Gruyter