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Items for "HPLC"

Measurement of arginine derivatives in pediatric patients with chronic kidney disease using high-performance liquid chromatography-tandem mass spectrometry

Background: The arginine derivatives asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) interfere with endothelial nitric oxide synthesis...

Keywords: arginine, asymmetric dimethylarginine, HPLC, Mass spectrometry, symmetric dimethylarginine

10/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Toward standardization of carbohydrate-deficient transferrin (CDT) measurements: I. Analyte definition and proposal of a candidate reference method

An alcohol-associated change in the serum transferrin glycoform pattern, carbohydrate-deficient transferrin (CDT), is used as a biomarker of chronic moderate to heavy alcohol consumption...

Keywords: alcohol biomarker, carbohydrate-deficient transferrin (CDT), disialotransferrin, HPLC, standardization

04/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Estimation of the limit of detection with a bootstrap-derived standard error by a partly non-parametric approach. Application to HPLC drug assays

A recently proposed procedure for estimating the limit of detection (LoD) of an assay using a partly non-parametric approach is applied to five HPLC drug assays...

Keywords: bootstrap, HPLC, limit of blank, limit of detection, non-parametric statistics, type I and II errors

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Evaluation of a novel semi-automated HPLC procedure for whole blood cyclosporin A confirms equivalence to adjusted monoclonal values from Abbott TDx

The problem in the measurement of cyclosporin (CyA) is that the widely used immuno-based assays suffer from interference by metabolites present in unpredictable excess...

Keywords: Abbott, cyclosporin, HPLC, liquid chromatography-mass spectrometry (LC-MS), metabolite interference, monoclonal, polyclonal

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Diagnostic efficiency of different amphetamine screening tests – the search for an optimal cutoff

Increased use of designer drugs (amphetamines and amphetamine-like substances) raises the need for fast screening tests in urine in clinical settings, workplace and drug rehabilitation...

Keywords: amphetamine, Axsym, cutoff, HPLC, screening test

09/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Determination of debrisoquine and 4-hydroxydebrisoquine by high-performance liquid chromatography: application to the evaluation of CYP2D6 genotype and debrisoquine metabolic ratio relationship

The drug-metabolizing cytochrome P450 (CYP) enzyme CYP2D6 is involved in the metabolism of several clinically important drugs...

Keywords: CYP2D6, debrisoquine, HPLC, metabolic ratio

03/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Improvement in HPLC separation of porphyrin isomers and application to biochemical diagnosis of porphyrias

Background: Identification of porphyrias relies on the measurement of different porphyrins in urine, feces and plasma...

Keywords: biochemical diagnosis, HPLC, porphyria, porphyrin

12/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
A robust liquid chromatography tandem mass spectrometry method for total plasma homocysteine determination in clinical practice

Background: Total plasma homocysteine has emerged as an independent risk factor for vascular disease...

Keywords: homocysteine, HPLC, tandem mass spectrometry (MS/MS), routine practice

08/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
External quality assessment of hemoglobin A2 measurement: data from an Italian pilot study with fresh whole blood samples and commercial HPLC systems

Background: To evaluate the extent of interlaboratory variation and accuracy in hemoglobin A2 (HbA2) assays, a pilot study of external quality assessment was organized among 48 Italian laboratories routinely measuring HbA2...

Keywords: external quality assessment scheme (EQAS), hemoglobin A2, HPLC, Quality Control, thalassemia

01/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
High-performance liquid chromatographic analysis of soluble and total oxalate in Ca- and Mg-amended liquid cultures of three wood decay fungi

Two brown-rot wood decay fungi, Fomitopsis pinicola and Meruliporia incrassata, and the white-rot species Phanerochaete chrysosporium were grown for 4 weeks in liquid culture at 0.35, 0.70, 1.05, and 5.00 mM calcium (Ca) and 1.35 and 2.70 mM magnesium (Mg) concentrations...

Keywords: Biodegradation, brown-rot, calcium, HPLC, oxalic acid, white-rot

10/2004 | Holzforschung, Walter de Gruyter
The effect of CaCl2 on growth rate, wood decay and oxalic acid accumulation in Serpula lacrymans and related brown-rot fungi

The dry rot fungus, Serpula lacrymans, is one of the most destructive copper-tolerant fungi causing timber decay in buildings in temperate regions...

Keywords: brown-rot fungi, calcium, CaCl2, copper citrate (CC), copper-based preservative, HPLC, oxalic acid, Serpula lacrymans, soil bottle test, wood decay

05/2006 | Holzforschung, Walter de Gruyter
Polycarboxylic acids as non-formaldehyde anti-swelling agents for wood

Wood specimens of fir (Abies alba Mill) and beech (Fagus sylvatica L.) were chemically modified using polycarboxylic acids (PCA), cured by convection heating or microwave treatment and analyzed by HPLC...

Keywords: 1,2,3,4-butanetetracarboxylic acid (BTCA), chemical modification, citric acid (CA), HPLC, microwave treatment, non-formaldehyde agents

07/2006 | Holzforschung, Walter de Gruyter
Screening fungi tolerant to Western red cedar (Thuja plicata Donn) extractives. Part 1. Mild extraction by ultrasonication and quantification of extractives by reverse-phase HPLC

Western red cedar (Thuja plicata Donn) heartwood samples were extracted in methanol...

Keywords: extractives, HPLC, lignan, quantification, tropolone, Western red cedar (Thuja plicata Donn)

03/2007 | Holzforschung, Walter de Gruyter