Items for "homocysteine thiolactone hypothesis"

The molecular basis of homocysteine thiolactone-mediated vascular disease

Accumulating evidence suggests that a metabolite of homocysteine (Hcy), the thioester Hcy-thiolactone, plays an important role in atherogenesis and thrombosis...

Keywords: atherosclerosis, autoantibodies, cystathionine ?-synthase (CBS), dietary hyperhomocysteinemia, fibrinogen, genetic hyperhomocysteinemia, homocysteine thiolactone hypothesis, immune activation, methylenetetrahydrofolate reductase (MTHFR), protein N-homocysteinylation, thrombosis