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Items for "HIV"

Analysis and Management of HIV Peptide Microarray Experiments

Objectives: To develop a tool for then easy and user-friendly management of peptide microarray experiments and for the use of the results of these experiments for the study the immune response against HIV virus infection in clinical samples. Methods: Applying bioinformatics and statistics for the analysis of data coming from microarray experiments as well as implementing a MIAME (Minimum Information About a Microarray Experiment) compliant database for managing and annotating experiments, results and samples. Results: We present a new tool for managing not only nucleic acid microarray experiments but also protein microarray experiments...

Keywords: Protein array analysis, HIV, serotyping, HIV infection, computational b

01/2006 | Methods of Information in Medicine, Schattauer

Competitive displacement of full-length HIV-1 Nef from the Hck SH3 domain by a high-affinity artificial peptide

We studied the interaction of the artificial 12-aa proline-rich peptide PD1 with the SH3 domain of the hematopoietic cell kinase Hck and the peptide's potency in competitively displacing HIV-1 Nef from the Hck SH3 domain...

Keywords: Competition, Hck, HIV, Nef, NMR, protein-peptide interaction, SH3

06/2007 | Biological Chemistry, Walter de Gruyter

Impact of genetic polymorphisms on the risk of lipid disorders in patients on anti-HIV therapy

Active anti-HIV therapy can induce hypertriglyceridemia, low high-density lipoprotein (HDL) and insulin resistance, eventually accompanied by clinical lipodystrophy, associated loss of subcutaneous adipose tissue and an increase in abdominal adiposity...

Keywords: antiretroviral therapy, apolipoprotein A-V, apolipoprotein C-III, apolipoprotein E, dyslipidemia, HIV, lipodystrophy, pharmacogenomics, protease inhibitors, tumor necrosis factor-? (TNF?)

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Simultaneous determination of HIV antibodies, hepatitis C antibodies, and hepatitis B antigens in dried blood spots –a feasibility study using a multi-analyte immunoassay

HIV in particular, as well as hepatitis B and C, present a burden on healthcare systems worldwide...

Keywords: dried blood spot, hepatitis, HIV, Luminex, sexually transmitted disease

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

?-Tocopherol as an antiretroviral therapy supplement for HIV-1-infected patients for increased lymphocyte viability

The aim of our study was to evaluate the benefits of supplementation with 800 mg/day of ?-tocopherol with regard to cellular viability in HIV-1 seropositive patients undergoing anti-retroviral therapy...

Keywords: antiretroviral therapy, Apoptosis, cellular viability, HIV, oxidative stress, ?-tocpherol

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

The epidemiology of preterm labor – a global perspective

The major burden of preterm birth is in the developing world, where much of the death and morbidity is secondary to infectious diseases such as malaria, HIV, tuberculosis and intestinal parasites...

Keywords: Bacterial vaginosis, ethnic group, HIV, malaria, pregnancy hypertension, preterm labor

07/2005 | Journal of Perinatal Medicine, Walter de Gruyter

Determination of CD4 lymphocyte percentages using a new simplified and affordable no lyse flow cytometric protocol: a pilot study / Bestimmung der Lymphozyten-abhängigen CD4-Prozentwerte mit Hilfe eines neuen, vereinfachten und kostengünstigen, durchfluss

Although the pathogenesis of HIV infection is independent of age, specific considerations have to be taken into account for the treatment of infants, children and adolescents...

Keywords: CD4, flow cytometry, HIV, paediatric, Durchflusszytometrie, pädiatrisch

05/2008 | LaboratoriumsMedizin, Walter de Gruyter

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