Items for "HepG2 cell"

Caspase-3 gene transfected with LIGHT gene: can it be used for therapy of human hepatocellular carcinoma?

Background: The aim of this study was to detect the expression of apoptosis factor caspase-3 in transferred HepG₂ cells and provide feasible evaluation of the treatment for primary liver cancer with gene methods.

Methods: The pcDNA4C-LIGHT cDNA was extracted from Escherichia coli JM-109; then, the pcDNA4C-LIGHT cDNA was transferred into the HepG₂ cells by a cationic liposome mediated method...

Keywords: CASPASE-3, Hepatocellular carcinoma, HepG2 cell, LIGHT gene, transfection