Items for "hepatitis C virus"

Determination of the hepatitis C virus subtype: comparison of sequencing and reverse hybridization assays

Background: Hepatitis C virus (HCV) genotyping and accurate subtyping is becoming increasingly relevant to epidemiological studies, clinical management, pathogenicity, and vaccine development.

Methods: The TRUGENE^® HCV 5?NC Genotyping Kit, the new VERSANT^® HCV Genotype 2.0 Assay (LiPA), and a new laboratory-developed HCV NS5b sequencing assay designed for automated sequencing of the HCV NS5b region were used...

Keywords: hepatitis C virus, NS5b, reverse hybridization, sequencing, subtype