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heparin
Items for "heparin"
The ability of different forms of heparins to suppress P-selectin function in vitro correlates to their inhibitory capacity on bloodborne metastasis in vivo
Ample evidence suggests that many of the in vivo anti-metastatic effects by heparins reflect their actions on P-selectin-mediated binding...
Keywords: anticoagulants, heparin, P-selectin, neoplasm metastasis, melanoma
03/2006 | Thrombosis and Haemostasis, SchattauerBiodistribution of covalent antithrombin-heparin complexes
We have developed a covalent antithrombin-heparin (ATH) complex with advantages compared to non-covalent antithrombin:heparin (AT:H) mixtures...
Keywords: Antithrombin, heparin, pharmacodynamics
04/2006 | Thrombosis and Haemostasis, SchattauerBenefit/risk profile of high-dose antithrombin in patients with severe sepsis treated with and without concomitant heparin
A randomised, prospective, placebo-controlled phase III multicentre clinical trial (KyberSept) has been performed to test the efficacy of high-dose antithrombin therapy in patients with severe sepsis...
Keywords: heparin, antithrombin III, severe sepsis, bleeding, survival
05/2006 | Thrombosis and Haemostasis, SchattauerIn vivo antithrombotic synergy of oral heparin and arginine: Endothelial thromboresistance without changes in coagulation parameters
On the basis of suggested clinical efficacy in an uncontrolled study in ninety-seven patients with unstable angina, an animal study was conducted to investigate antithrombotic synergy between orally administered heparin and arginine...
Keywords: heparin, thrombosis, endothelium, arginine, oral
05/2006 | Thrombosis and Haemostasis, SchattauerEarly in vivo anticoagulation inhibits the angiogenic response following hindlimb ischemia in a rodent model
Emerging findings have demonstrated the critical role of blood clotting factors in the formation and stabilization of embryonic blood vessels...
Keywords: Angiogenesis, warfarin, hirudin, heparin, Anticoagulant
07/2006 | Thrombosis and Haemostasis, SchattauerInitial treatment of venous thromboembolism
Immediate anticoagulant treatment is essential to reduce morbidity and mortality in patients with acute venous thromboembolism (VTE)...
Keywords: Venous thromboembolism, deep vein thrombosis, pulmonary embolism, heparin, Low-molecular-weight heparin, anticoagulants
09/2006 | Thrombosis and Haemostasis, SchattauerMonitoring unfractionated heparin with the aPTT: Time for a fresh look
Laboratory monitoring is widely recommended to measure the anticoagulant effect of unfractionated heparin and to adjust the dose to maintain levels in the target therapeutic range...
Keywords: heparin, laboratory monitoring, aPTT
11/2006 | Thrombosis and Haemostasis, SchattauerManagement of cutaneous type IV hypersensitivity reactions induced by heparin
Localized hypersensitivity reactions to subcutaneous heparin injections have been described since 1952...
Keywords: heparin, inflammation, pharmacology, allergy
11/2006 | Thrombosis and Haemostasis, SchattauerFucosylated chondroitin sulfate as a new oral antithrombotic agent
Fucosylated chondroitin sulfate is a potent anticoagulant polysaccharide extracted from sea cucumber...
Keywords: Glycosaminoglycans, fucosylated chondroitin sulfate, oral anticoagulants, heparin
12/2006 | Thrombosis and Haemostasis, SchattauerIFCC Guideline for sampling, measuring and reporting ionized magnesium in plasma
Analyzers with ion-selective electrodes (ISEs) for ionized magnesium (iMg) should yield comparable and unbiased results for iMg...
Keywords: erythrocyte effect, heparin, influence factors, interference, ionized calcium, ionized magnesium, ion-selective electrode, lipophilic anions, liquid junction potential, pH, protein, sampling, silicone, sodium
01/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterGuidelines for sampling, measuring and reporting ionized magnesium in undiluted serum, plasma or blood: International Federation of Clinical Chemistry and Laboratory Medicine (IFCC): IFCC Scientific Division, Committee on Point of Care Testing
All analyzers with ion-selective electrodes for ionized magnesium (iMg) should yield comparable and unbiased results...
Keywords: erythrocyte, heparin, influence factors, interference, ionized calcium, ionized magnesium, ion-selective electrode, lipophilic anions, liquid junction potential, pH, protein, sampling, silicone, sodium
05/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterPlasma or serum samples: measurements of cardiac troponin T and of other analytes compared
Conflicting data in the literature concern possible differences in the immunochemical measurement of cardiac troponins, either in plasma or in serum...
Keywords: cardiac markers, heparin, Plasma, serum, troponins
08/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterLithium heparinised blood-collection tubes give falsely low albumin results with an automated bromcresol green method in haemodialysis patients
Keywords: Albumin, bromcresol green, bromcresol purple, haemodialysis, heparin
03/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter