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Items for "Heart failure"

Cardiac resynchronisation therapy: Effects on myocardial perfusion at rest, after vasodilation and oxygen consumption

Aim: Cardiac resynchronisation therapy (CRT) has been shown to improve haemodynamics and clinical symptoms in heart failure patients...

Keywords: Herzinsuffizienz, Linksschenkelblock, Perfusion, Sauerstoffverbrauch, PET

01/2006 | Nuklearmedizin, Schattauer
Determination of ventricular volumes in coronary artery disease: Comparison of two gated SPECT analysis tools with MRI

Aim: Comparison of two gated SPECT analysis tools gated SPECT quantification (GSQ) and emory cardiac toolbox (ECT) in patients with coronary artery disease (CAD) and severely impaired left ventricular function (preoperative: EF <35% by cardiac catheter)...

Keywords: GatedSPECT, kardiale Volumetrie, kardiale MRT, Myokardnarbe, koronare Herzerkrankung, Herzinsuffizienz

01/2006 | Nuklearmedizin, Schattauer
Use of a solid-phase extraction with radioimmunoassay to identify the proportional bias of clinical B-type natriuretic peptide immunoassay: the impact of plasma matrix and antibody multispecificity

Background: Circulating immunoreactive B-type natriuretic peptide-32 (ir-BNP-32) has diagnostic and prognostic values in heart failure...

Keywords: antibody multispecificity, Heart failure, plasma immunoreactive BNP-32, point-of-care test, radioimmunoassay, solid-phase extraction

10/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Atrial natriuretic peptide and related peptides

In recent years, biomarkers have been recognized as important tools for diagnosis, risk stratification, and therapeutic decision-making in cardiovascular diseases...

Keywords: Acute coronary syndrome, atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis natriuretic peptide (DNP), Heart failure, renal failure

10/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Analytical and clinical performance of three natriuretic peptide tests in the emergency room

Background: The aim of the present study was to investigate the analytical and diagnostic utility of B-type natriuretic peptide (BNP) and the N-terminus of this prohormone, N-terminal pro-BNP (NT-pro-BNP) testing in the emergency department to identify acute congestive heart failure (CHF).

Methods: A blood sample taken from patients presenting to the emergency department with acute dyspnoea (n=80) was analyzed for natriuretic peptides using three different assays [Triage BNP (Biosite), Centaur BNP (Bayer) and Elecsys NT-pro-BNP (Roche)]...

Keywords: diagnosis, dyspnoea, Heart failure, natriuretic peptides, renal failure

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Transesophageal left ventricular posterior wall potential in heart failure patients with biventricular pacing / Transsophageales linksventrikulres Potenzial der posterioren Wand bei Patienten mit Herzinsuffizienz und biventrikulrer Stimulation

Introduction: Biventricular (BV) pacing is an established therapy for heart failure (HF) patients with intraventricular conduction delay, but not all patients improved clinically...

Keywords: biventricular pacing, cardiac resynchronization, Heart failure, interventricular delay, left ventricular electrocardiography, biventrikulre Stimulation, Herzinsuffizienz, interventrikulres Delay, kardiale Resynchronisation, linksventrikulre Elektrographie

04/2007 | Biomedizinische Technik, Walter de Gruyter
Expressed genome molecular signatures of heart failure

Traditional gene expression studies typically focus on one or a few genes of interest...

Keywords: cardiovascular diseases, gene expression profile, Heart failure, microarray

05/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Long-term stability of endogenous B-type natriuretic peptide (BNP) and amino terminal proBNP (NT-proBNP) in frozen plasma samples

The aim of the present study was to assess the long-term stability of endogenous B-type natriuretic peptide (BNP) and amino terminal proBNP (NT-proBNP) in plasma samples stored at –20°C without addition of protease inhibitors (e.g., aprotinin)...

Keywords: Evaluation, Heart failure, natriuretic peptides, Plasma, stability

08/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Analytical evaluation of the Dade Behring Dimension RxL automated N-Terminal proBNP (NT-proBNP) method and comparison with the Roche Elecsys 2010

Methods to quantify B-type natriuretic peptide (BNP) and N-terminal-propeptide (NT-proBNP) in plasma or serum samples are well established...

Keywords: brain natriuretic peptide (BNP), Heart failure, natriuretic peptides, N-terminal proBNP (NT-proBNP)

11/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Analytical performance and clinical results of a fully automated MEIA system for brain natriuretic peptide assay: comparison with a point of care testing method

The aim of this study was to evaluate the analytical performance of a recently available immunoassay for brain natriuretic peptide (BNP), based on microparticle enzyme immunoassay (MEIA, AxSYM System, Abbott Laboratories), whose analytical characteristics and clinical results were compared with those of a point of care testing (POCT) method (TRIAGE system, Biosite Diagnostics)...

Keywords: brain natriuretic peptide, cardiac natriuretic hormones, Heart failure, microparticle enzyme immunoassay system, point of care testing method

10/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Concentrations of N-terminal pro-brain natriuretic peptide and troponin T in plasma of 75-year-old apparently healthy persons

Clinical chemical reference values for older persons are sparse and mostly intermixed with those for younger persons...

Keywords: Heart failure, N-terminal pro-brain natriuretic peptide (NT-proBNP), prognostic marker, reference interval, troponin T

12/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Homocysteine and heart failure: a review of investigations from the Framingham Heart Study

High plasma homocysteine levels are associated with a moderately increased risk of cardiovascular disease, particularly of atherosclerotic events...

Keywords: epidemiology, Heart failure, homocysteine, left ventricular hypertrophy

10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Increased homocysteine in heart failure: a result of renal impairment?

Background: Hyperhomocysteinemia may constitute a risk factor for patients with severe heart failure...

Keywords: Heart failure, hyperhomocysteinemia, renal function

11/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Ischemia-modified albumin and NT-prohormone-brain natriuretic peptide in peripheral arterial disease

Cardiovascular disease is the leading cause of mortality and morbidity in Western countries...

Keywords: Heart failure, ischemia-modified albumin, myocardial ischemia, natriuretic peptides, Peripheral arterial disease

02/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Clinical relevance of biological variation: the lesson of brain natriuretic peptide (BNP) and NT-proBNP assay

The clinical relevance of brain natriuretic peptide (BNP) and N-terminal (NT)-proBNP assays as a diagnostic tool and prognostic marker in patients with cardiovascular diseases has recently been confirmed...

Keywords: Acute coronary syndrome, atrial natriuretic peptide (ANP), biological variation, brain natriuretic peptide (BNP), cardiac function, cardiac natriuretic hormones, cardiovascular diseases, Heart failure

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Prognostic value of homocysteinemia in patients with congestive heart failure

Background: Elevated plasma homocysteine levels are associated with increased risk of vascular disease and of congestive heart failure (CHF), with a relationship between homocysteine values and disease severity...

Keywords: ejection fraction, Heart failure, homocysteinemia, NYHA classification, Prognosis

07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Clinical relevance of non-cardiac determinants of natriuretic peptide levels

There is evidence that natriuretic peptide (namely atrial and/or B-type natriuretic peptides) plasma concentration may be elevated in many clinical conditions besides cardiovascular diseases, the most frequent being lung diseases, renal and liver failure, acute cerebrovascular events, acute and chronic inflammatory diseases and certain metabolic and endocrine disorders...

Keywords: diagnostic accuracy, Heart failure, natriuretic peptides, renal failure

11/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Natriuretic peptide testing in primary care patients

The evaluation of cardiac endocrine function by means of automated robust assays has permitted the introduction of a cheap and powerful clinical tool...

Keywords: B-type natriuretic peptides, diagnosis, Heart failure, primary care, Prognosis, screening

11/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Coenzyme Q10 and high-sensitivity C-reactive protein in ischemic and idiopathic dilated cardiomyopathy

Background: Cardiomyopathy (CMP) is a common debilitating illness, associated with a high mortality and poor quality of life...

Keywords: antioxidants, Cardiomyopathy, coenzyme Q10, C-reactive protein, Heart failure, oxidative stress

03/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Free fatty acids as a cardiovascular risk factor

Free fatty acids (FFAs) serve as physiologically important energy substrates and their release from the adipose tissue by lipolysis is regulated according to the energy demands of the body...

Keywords: atherosclerosis, cardiovascular diseases, epidemiology, free fatty acids (FFAs), Heart failure, non-esterified fatty acids (NEFAs)

04/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Genetic deficiency in tissue kallikrein activity in mouse and man: effect on arteries, heart and kidney

Tissue kallikrein (KLK1) is a kinin-forming serine protease synthesized in many organs including arteries and kidney...

Keywords: cardiac ischemia, diabetic nephropathy, endothelial function, Heart failure, ion transport, vasodilatation

06/2008 | Biological Chemistry, Walter de Gruyter
Side effects of angiotensin converting enzyme inhibitor (captopril) in newborns and young infants

Aim: To analyze the side effects of captopril, an angiotensin converting enzyme inhibitor (ACEI) in newborn and young infants.

Methods: Retrospective analysis of side effects in 43 patients with congenital heart disease after cardiac surgery treated with captopril for heart failure during a two-year period.

Results: Median age of the patients was 26 days (range 6–310 days), median weight 3.5 kg (range 1.9–7.9 kg)...

Keywords: Angiotensin converting enzyme inhibitor, Heart failure, hypotension, infant, Newborn, renal failure

09/2008 | Journal of Perinatal Medicine, Walter de Gruyter