Items for "haptoglobin phenotypes"

Influence of human haptoglobin polymorphism on oxidative stress induced by free hemoglobin on red blood cells

Background: An in vitro study was conducted to determine whether haptoglobin phenotypes differed in their protective effect against oxidative stress induced by extracellular hemoglobin on red blood cells.

Methods: Conjugated dienes and thiobarbituric acid-reactive substances (TBARS) were determined in human red blood cell membranes in the presence of hemoglobin and various concentrations of each type of purified haptoglobin...

Keywords: haptoglobin phenotypes, hemoglobin, hemolysis, oxidative stress, red blood cell membranes