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Items for "haemostasis"

Haemostasis and antithrombotic drugs: pharmacology and novel therapeutic approaches

Considerable progress has been made during the last years with the development of new antiplatelet and antithrombotic agents...

Keywords: Antithrombotika, Hämostase

01/2006 | Hämostaseologie, Schattauer
Perioperative management of coagulation

Guidelines of official societies for diagnosis and therapy of intraoperatively occurring hypocoagulability rely mainly on data of patients receiving whole blood transfusions...

Keywords: Hämostase, Labormethoden, PT, aPTT, Fibrinogen, Blutverlust, Volumentherapie, Thrombelastographie/Thrombelastometrie, TEG, ROTEM

01/2006 | Hämostaseologie, Schattauer
Haemostasis and pregnancy

Normal pregnancy is associated with profound alterations in the coagulation and fibrinolytic systems...

Keywords: haemostasis, Thrombophilia, bleeding, pregnancy

03/2006 | Thrombosis and Haemostasis, Schattauer
Genetic influences on fibrinogen, tissue plasminogen activatorantigen and von Willebrand factor in males and females

Differences in genetic influence on death from CHD between males and females have been reported. Haemostatic factors have consistently been associated with risk for coronary heart disease (CHD), but sex differences in genetic architecture have not been studied...

Keywords: Twins, haemostasis, heritability, sex differences, oral contraceptive pill

03/2006 | Thrombosis and Haemostasis, Schattauer
Does a coxib-associated thrombotic risk limit the clinical use of the compounds as analgesic, antiinflammatory drugs? Arguments against

The issue of the risk-benefit assessment of cyclooxygenase-2 (COX-2) inhibitors, as compared to traditional non-steroidal anti-inflammatory drugs (tNSAIDs), is far from being resolved...

Keywords: arterial thrombosis, lipid mediators, inflammation, haemostasis, Clinical studies

10/2006 | Thrombosis and Haemostasis, Schattauer
Thrombin activation of endometrial endothelial cells: A possible role in intrauterine growth restriction

Preeclampsia (PE), intrauterine growth restriction (IUGR) and abruption with or without fetal loss are associated with reduced uteroplacental blood flow, decidual vasculopathy, endothelial cell dysfunction, thrombosis, inflammation and hemorrhage...

Keywords: Angiogenesis and inhibitors, pregnancy, inflammation, haemostasis, cytokines

00/0000 | Thrombosis and Haemostasis, Schattauer
Interaction of an annexin V homodimer (Diannexin) with phosphatidylserine on cell surfaces and consequent antithrombotic activity

Annexin V (AV), a protein with anticoagulant activity, exerts antithrombotic activity by binding to phosphatidylserine (PS), inhibiting activation of serine proteases important in blood coagulation...

Keywords: phospholipids, annexins, haemostasis

03/2007 | Thrombosis and Haemostasis, Schattauer