Items for "GPI-anchored"

Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17

Metalloproteases play a complex role in tumor progression. While the activity of some ADAM, ADAMTS and matrix metalloproteases (MMPs) seems to be protumorigenic, the activity of others seems to prevent tumor progression...

Keywords: extracellular matrix, GPI-anchored, metalloprotease, oncogenesis, proteomics, shedding