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Items for "glutathione"

Relationship between neurological outcome and early oxidative changes in erythrocytes in head injury patients

Background: Experimental data indicate that destructive oxidative events reach their peak within the first 24 h after trauma in head injury (HI) and that brain damage occurring due to this impact can be the cause of death or irreversible permanent disabilities in affected patients.

Methods: Venous blood samples were obtained from 50 HI patients within 24 h of trauma onset and from 30 age- and sex-matched normal controls (NC)...

Keywords: erythrocytes, glutathione, lipid peroxidation, outcome, reactive oxygen species

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

The significance of serum ?-glutamyltransferase in cardiovascular diseases

Since early after the introduction of serum ?-glutamyltransferase (GGT) in clinical practice as a reliable and widely employed laboratory test, epidemiological and prospective studies have repeatedly shown that this activity possesses a prognostic value for morbidity and mortality...

Keywords: atherosclerosis, glutathione, myocardial infarction, serum ?-glutamyltransferase, Stroke

10/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Elevated plasma cysteinylglycine levels caused by cilastatin-associated antibiotic treatment

Imipenem (thienamycin formamidine), a broad-spectrum ?-lactam antibiotic, is always used in combination with cilastatin in order to avoid the premature breakdown of imipenem by renal tubular dipeptidase...

Keywords: aminothiols, cilastatin, cysteine, cysteinylglycine, glutathione, imipenem

03/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Increased fructosamine in non-diabetic rheumatoid arthritis patients: role of lipid peroxides and glutathione

Modification of proteins by non-enzymatic glycation is one of the underlying factors known to play a major role in the pathogenesis of many clinical disorders...

Keywords: fructosamine, glutathione, malondialdehyde, rheumatoid arthritis

07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Methionine metabolism in an animal model of sepsis

Background: Sepsis is a disease with high incidence and lethality and is accompanied by profound metabolic disturbances...

Keywords: S-adenosylmethionine, DNA methylation, homocysteine metabolism, glutathione, oxidative stress, sepsis, transmethylation

10/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter