Items for "glucosylceramide"

Acid ?-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy

In mammalian cells, glucosylceramide (GlcCer), the simplest glycosphingolipid, is hydrolyzed by the lysosomal enzyme acid ?-glucosidase (GlcCerase)...

Keywords: Gaucher disease, glucosylceramide, lysosome, X-ray structure