Fatty acid derivatisation was used to develop two novel, long-acting, N-terminally modified, glucose-dependent insulinotropic polypeptide (GIP) analogues,
Keywords: dipeptidylpeptidase IV (DPP IV), fatty acid derivatisation, GIP analogues, glucose-dependent insulinotropic polypeptide (GIP), insulin secretion, obese diabetic ob/ob mice
07/2005 | Biological Chemistry, Walter de GruyterIncretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are intestinal hormones that are released in response to ingestion of nutrients, especially carbohydrate...
Keywords: adipose tissue, ?-cells, bone, brain, diabetes, dipeptidyl peptidase IV (DPPIV), exendin-4, glucagon-like peptide 1 (GLP-1), glucose, glucose-dependent insulinotropic polypeptide (GIP), incretins, insulin, liver, metabolism
01/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterGlucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone secreted by endocrine K-cells in response to nutrient absorption...
Keywords: GIP analogue, glucagon, glucose-dependent insulinotropic polypeptide (GIP), islet
02/2008 | Biological Chemistry, Walter de Gruyter