Items for "glomerular filtration rate"

Multicentre physiological reference values for the concentration of creatininium in plasma and diagnostic specificity of glomerular filtration rate estimated with the MDRD equation

Background: The National Kidney Disease Education Program recommends that clinical laboratories, when asked for an estimation of glomerular filtration rate in a patient by means of the “four-variable” Modification of Diet in Renal Disease (MDRD) Study equation, also provide the measurement result for creatininium concentration in plasma and the appropriate reference interval...

Keywords: chronic kidney disease, creatininium, glomerular filtration rate, Modification of Diet in Renal Disease (MDRD) equation, multicentre reference values, physiological reference intervals

Analysis of glomerular filtration rate, serum cystatin C levels, and renal resistive index values in cirrhosis patients

Background: The aim of this study was to evaluate the relation of glomerular filtration rate (GFR) to serum cystatin C levels, renal resistive index (RRI), serum creatinine and creatinine clearance in patients with different stages of cirrhosis.

Methods: The study sample was 25 cirrhotic patients (10 females and 15 males; mean age 57.3±2.04 years), 10 in the compensated stage without ascites and 15 in the decompensated stage with new-onset ascites...

Keywords: ascites, glomerular filtration rate, liver cirrhosis stage, renal resistive index, serum cystatin C

The importance of metrological traceability on the validity of creatinine measurement as an index of renal function: International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)

The glomerular filtration rate (GFR) is currently considered the best overall index of kidney function...

Keywords: calibration, creatinine, glomerular filtration rate, kidney function tests, reference standards, traceability

Laboratory evaluation of kidney function in the elderly¹

Demographic changes and the increasing proportion of elderly among the overall population call for consideration of the morphology and function of the ageing kidney...

Keywords: glomerular filtration rate, renal biomaker

A new serum cystatin C-based equation for assessing glomerular filtration rate in liver transplantation

Background: Cystatin C (CysC) has been identified to be an alternative marker of glomerular filtration rate (GFR), but no CysC-based equation has been developed for patients receiving liver transplantation.

Methods: Serum CysC and ^99mTc-DTPA clearance (true GFR) were measured simultaneously on post-transplant days 1, 4 and 7...

Keywords: Bland and Altman analysis, cystatin C, DTPA clearance, glomerular filtration rate, Liver transplantation

Trueness verification of actual creatinine assays in the European market demonstrates a disappointing variability that needs substantial improvement. An international study in the framework of the EC4 creatinine standardization working group

Background: The European In Vitro Diagnostics (IVD) directive requires traceability to reference methods and materials of analytes...

Keywords: analytical error, bias, calibration, creatinine, External Quality Assessment, glomerular filtration rate, reference methods

Intra-individual variation in creatinine and cystatin C

Background: Serum creatinine and cystatin C are measured in the assessment of glomerular filtration rate...

Keywords: creatinine, cystatin C, glomerular filtration rate, intra-individual variation