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Items for "gingipains"

Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR

Heme utilization in Porphyromonas gingivalis requires the participation of an outer membrane hemin/hemoglobin receptor, HmuR, the lysine-specific gingipain proteinase (Kgp) and arginine-specific gingipain proteinase (Rgp)...

Keywords: Gene expression, gingipains, heme receptor, Porphyromonas gingivalis

11/2004 | Biological Chemistry, Walter de Gruyter
Mechanism of methaemoglobin breakdown by the lysine-specific gingipain of the periodontal pathogen Porphyromonas gingivalis

The R- and K-gingipain proteases of Porphyromonas gingivalis are involved in proteolysis of haemoglobin from which the defensive dimeric haem pigment is formed...

Keywords: gingipains, haem, haemoglobin, periodontal disease, Porphyromonas, protease

09/2008 | Biological Chemistry, Walter de Gruyter