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Items for "genetics"
Stroke: epidemiology, risk factors, and genetics
Stroke constitutes a major global challenge for health policy and healthcare economics. Reducing stroke burden requires extensive knowledge of risk factors and, if applicable, preventive control...
Keywords: Schlaganfall, Epidemiologie, Risikofaktoren, Genetik
01/2006 | Hämostaseologie, SchattauerGenetic Epidemiology in Germany From Biobanking to Genetic Statistics
Objectives: Genetic epidemiology investigates the role of genetic factors and their interaction with environmental factors (in a broad meaning) for the occurrence of diseases in human populations...
Keywords: Biobanking, genetics, epidemiology, bioethics
01/2005 | Methods of Information in Medicine, SchattauerGenetic analysis of CAV1 gene in hypertension and metabolic syndrome
Recently, we reported that the polymorphism 1132T>C (Gene-Bank: AF519768.1) of the NOS3 gene was associated with susceptibility to metabolic syndrome (MS) in hypertensive patients...
Keywords: CAV1, MNOS3, genetics, hypertension, metabolic syndrome
04/2006 | Thrombosis and Haemostasis, SchattauerHaplotypes of the plasminogen activator gene associated with ischemic stroke
Ischemic stroke (IS) is thought to be a multifactorial disorder associated with genetic backgrounds and environmental factors...
Keywords: Tissue plasminogen activator, ischemic stroke, haplotypes, association studies, genetics
09/2006 | Thrombosis and Haemostasis, SchattauerIdentification of functional polymorphisms of the thromboxane A2 receptor gene in healthy volunteers
Thromboxane A2 receptor (TP) is an important actor in vascular physiology and plays a crucial role in the platelet activation process...
Keywords: genetics, Platelet, polymorphisms, thromboxane, TP
09/2006 | Thrombosis and Haemostasis, SchattauerAssessment of genetic risk for myocardial infarction
Although lifestyle and environmental factors influence the prevalence of myocardial infarction, genetic epidemiological studies have suggested that several genetic variants increase the risk for this condition...
Keywords: genetics, Polymorphism, myocardial infarction, coronary heart disease, atherosclerosis
08/2006 | Thrombosis and Haemostasis, SchattauerFibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: The Rotterdam Study
Fibrin network structure has been correlated with coronary disease. Fibrinogen and (FGG and FGA) gene haplotypes (chromosome 4q28) may be associated with fibrin network structure, and thereby with rigidity of the fibrin clot and sensitivity of the fibrin clot to the fibrinolytic system...
Keywords: Coronary disease, atherosclerosis, epidemiology, genetics, fibrinogen
00/0000 | Thrombosis and Haemostasis, SchattauerDistribution, morphology, and genetic affinities of dwarf embedded Fucus populations from the Northwest Atlantic Ocean
Dwarf embedded
Keywords: distribution, dwarf embedded Fucus, ecology, genetics, morphology, salt marsh fucoid algae
09/2006 | Botanica Marina, Walter de GruyterUnderstanding hyperlipidemia and atherosclerosis: lessons from genetically modified
apoe and
ldlr mice
Hyperlipidemia is the most important risk factor for atherosclerosis, which is the major cause of cardiovascular disease...
Keywords: apolipoprotein E (ApoE), gene targeting, genetics, Genomics, hyperlipoproteinemia, low-density protein receptor (LDLR), transgenesis
05/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterNutrigenomics – 2006 update
The Human Genome and HapMap projects have provided the tools and information that will aid in understanding how nutrients alter the expression of an individual's genetic information and why individuals differ in metabolism of foods at the molecular level...
Keywords: Epistasis, gene-nutrient interactions, genetics, nutrigenomics, nutrition
03/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterMother-to-infant vertical transmission of transfusion transmitted virus in South China
A nested PCR was used to detect TTV DNA in serum from 490 mother-infant pairs to determine the rate of vertical transmission of TTV in Guangzhou City, P.R...
Keywords: genetics, infant, nested polymerase chain reaction, pregnancy, transfusion transmitted virus, vertical transmission
09/2004 | Journal of Perinatal Medicine, Walter de GruyterA pediatric perspective on hemochromatosis: not just “an old man's disease” Eine pädiatrische Sichtweise der Hämochromatosis: nicht nur ein Altersleiden
Hemochromatosis, once considered to be an autosomal recessive disorder of increased iron absorption, predominantly affecting men after the fourth decade of life, is now known to be a syndrome caused by mutations in at least five different genes, one of which results in an autosomal dominant form of the disease...
Keywords: Genetik, Hämochromatose, juvenil, Kind
03/2006 | LaboratoriumsMedizin, Walter de GruyterBiobanks in Genetic-epidemiological Research such as KORA-gen
Biobanks are an important tool of genetic epidemiology, which investigates the role of genetic factors and their interaction with environmental factors (in a broad meaning) for the occurrence of diseases in human populations...
Keywords: biobanks, genetics, epidemiology, biostatistics, bioethics
06/2007 | it – Information Technology (vormals it+ti), Oldenbourg Wissenschaftsverlag