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You are here: Home :: Keyword index :: eth bis gen :: Genetic Evolution - genotype-phenotype correlation genetic susceptibility

Items for "genetic susceptibility"

Association analysis of hepatitis virus B infection with haplotypes of the TBX21 gene promoter region in the Chinese population

Background: The T-box21 (TBX21) gene encodes the transcription factor T-bet (T-box expressed in T-cells), which influences naive T-lymphocyte development and has been implicated in the pathogenesis of many diseases.

Methods: We selected 208 hepatitis B patients and 213 healthy volunteers to examine whether polymorphisms or haplotypes of the TBX21 gene promoter were associated with hepatitis B virus (HBV) infection in the Chinese population...

Keywords: genetic susceptibility, haplotype, hepatitis B virus (HBV), promoter, TBX21 (T-box21) gene

03/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Apolipoprotein E polymorphisms in Mexican patients with coronary artery disease

Background: Apolipoprotein E polymorphisms have important effects on plasma lipid levels and in the genetic susceptibility to development of cardiovascular diseases...

Keywords: apolipoprotein E, coronary artery disease, genetic susceptibility, Mexican population, Polymorphism

04/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Genes and the preeclampsia syndrome

Preeclampsia is specific to pregnancy and is still a leading cause of maternal and perinatal mortality and morbidity, affecting about 3% of women, but the underlying pathogenetic mechanisms still remain unclear...

Keywords: Candidate genes, genetic susceptibility, linkage, preeclampsia

01/2008 | Journal of Perinatal Medicine, Walter de Gruyter