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You are here: Home :: Keyword index :: eth bis gen :: Genetic Evolution - genotype-phenotype correlation genetic polymorphisms

Items for "genetic polymorphisms"

High-sensitivity C-reactive protein concentration in patients with myocardial infarction-environmental factors, and polymorphisms in interleukin-10 and CD14 genes

Background: It has been shown that high-sensitivity C-reactive protein (hsCRP) concentrations are associated with elevated risk of myocardial infarction, but the mechanisms regulating hsCRP concentration are not completely elucidated yet...

Keywords: atherosclerosis, CD14, environmental factors, genetic polymorphisms, interleukin-10, myocardial infarction

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
A1166C polymorphism of the angiotensin AT1 receptor (AT1R) gene alters endothelial response to statin treatment

Background: The function of vascular endothelium is influenced by several factors: low-density lipoprotein (LDL) cholesterol, oxidative stress and the reninangiotensin system.

Methods: We tested the hypothesis that polymorphisms A1166C of the angiotensin AT1 receptor (AT1R) gene, C242T and A640G of the pphox22 gene (p22 phox is an essential component of NADH/NADPH oxidases) and G894T of the endothelial nitric oxide (NO) synthase (eNOS) gene influence endothelial function and its reaction to statin treatment...

Keywords: genetic polymorphisms, statin treatment, vascular endothelium

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter