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Items for "gene polymorphism"

Gender differences in the expression of erythrocyte aggregation in relation to B-fibrinogen gene polymorphisms in apparently healthy individuals

An increased erythrocyte aggregation (EA) is associated with capillary slow flow, tissue hypoxemia and endothelial dysfunction...

Keywords: Erythrocyte aggregation, fibrinogen, gene polymorphism

03/2006 | Thrombosis and Haemostasis, Schattauer

Apolipoprotein A-V gene polymorphisms in subjects with metabolic syndrome

Background: Genetic variation at the apolipoprotein A-V locus, recently discovered proximal to the APOA1/C3/A4 gene cluster, is associated with elevated triglyceride concentrations, a risk factor for atherosclerosis.

Methods: The goal of our study was to determine the association of two apolipoprotein A-V (APOA5) gene polymorphisms in a group of urban Romanian subjects with the prevalence of the metabolic syndrome...

Keywords: apolipoprotein A-V, gene polymorphism, metabolic syndrome, obesity

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Rapid detection of the factor XIII Val34Leu (163 G?T) polymorphism by real-time PCR using fluorescence resonance energy transfer detection and melting curve analysis

The Val34Leu polymorphism in the A subunit of blood coagulation factor XIII (FXIII-A) is located in the activation peptide, just three amino acids upstream of the thrombin cleavage site...

Keywords: factor XIII, fluorescence resonance energy transfer, gene polymorphism, real-time PCR

08/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

APOA1 polymorphisms are associated with variations in serum triglyceride concentrations in hypercholesterolemic individuals

Background: Apolipoprotein A-I gene (APOA1) polymorphisms have been associated with variations in serum low-density lipoprotein (LDL)- and high-density lipoprotein (HDL)-cholesterol...

Keywords: apolipoprotein A-I, atorvastatin, gene polymorphism, hypercholesterolemia, triglyceride

12/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Association study between fibronectin and coronary heart disease

Fibronectin is a known chemoattractant for several cell types that play a role in the wound healing process, including fibroblasts, endothelial cells and macrophages...

Keywords: atherosclerosis, coronary heart disease, fibronectin, gene polymorphism, plasma fibronectin

01/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Association of angiotensin II type 1 receptor gene polymorphism with carotid atherosclerosis

Background: Polymorphisms of the angiotensin II type 1 receptor (AGTR1) gene are associated with essential hypertension and cardiovascular disease, but the correlation between AGTR1 A1166C polymorphism and carotid intima-media thickness (IMT) remains unclear...

Keywords: angiotensin II type 1 receptor, atherosclerosis, carotid artery, essential hypertension, gene polymorphism

03/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

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