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Gene expression
Items for "Gene expression"
An Appraoch to Dynamic Modelling of Gene Expression by Zhegalkin Polynomials
A new approach to modelling gene expression dynamics is presented. Unlike other modelling approaches, the presented method can cope with both: discrete biological rules, namely the canalizing property of gene interaction as well as continuous measurement data...
Keywords: Gene expression, microarray data, Zhegalkin polynomials
12/2005 | at – Automatisierungstechnik, Oldenbourg WissenschaftsverlagTwo-color Microarray Experiments. Technology and Sources of Variance
OBJECTIVES: Microarray gene expression experiments have a complex technical background. Knowledge about certain technical details is inevitable to judge alternatives for both experimental design and analysis...
Keywords: Agilent, chip, comparative hybridization, Gene expression, microarray, technical variance
01/2005 | Methods of Information in Medicine, SchattauerEstimating the Number of Clusters in DNA Microarray Data
Objectives: The main objective of the research is an application of the clustering and cluster validity methods to estimate the number of clusters in cancer tumor datasets...
Keywords: Gene expression, Data Mining, clustering, cluster evaluation, validity indices
01/2006 | Methods of Information in Medicine, SchattauerCoordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR
Heme utilization in
Keywords: Gene expression, gingipains, heme receptor, Porphyromonas gingivalis
11/2004 | Biological Chemistry, Walter de GruyterHypoxia and lipid signaling
Sufficient oxygen supply is crucial for the development and physiology of mammalian cells and tissues...
Keywords: eicosanoids, Gene expression, hypoxia, hypoxia-inducible factor, signal transduction, sphingolipids
10/2006 | Biological Chemistry, Walter de GruyterPrognostic significance of the expression of SR-A1 , encoding a novel SR-related CTD-associated factor, in breast cancer
SR-A1 is a human high-molecular-weight SR-related CTD-associated factor that links the machineries of transcription and mRNA splicing...
Keywords: biomarkers, breast cancer, Gene expression, Prognosis, SCAFs, splicing factors, SR proteins
12/2006 | Biological Chemistry, Walter de GruyterMolecular and functional analysis of new members of the wheat PR4 gene family
Five new genes belonging to the pathogenesis-related (PR) 4 family have been cloned and characterised in
Keywords: defence genes, functional gene promoter, Gene expression, PR4 genes, promoter analysis, SAR inducers
08/2006 | Biological Chemistry, Walter de GruyterTissue-specific transcription factor HNF4? inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 ?-cell line
Hepatocyte nuclear factor 4? (HNF4?) is a tissue-specific transcription factor expressed in many cell types, including pancreatic ?-cells...
Keywords: cell multiplication, endocrine pancreas, Gene expression, MODY1, tetracycline induction
01/2007 | Biological Chemistry, Walter de GruyterMid-region parathyroid hormone-related protein (PTHrP) and gene expression of MDA-MB231 breast cancer cells
We have previously shown that PTHrP(38–94) amide restrains growth and invasion
Keywords: breast cancer, differential display, Gene expression, PCR, PTHrP
05/2007 | Biological Chemistry, Walter de GruyterExpression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway
KEPI is a protein kinase C-potentiated inhibitory protein for type 1 Ser/Thr protein phosphatases...
Keywords: breast tumorigenesis, EGR1, ERK, Gene expression, KEPI, PTEN
05/2007 | Biological Chemistry, Walter de GruyterA quantitative RT-PCR method to determine topoisomerase I mRNA levels in human tissue samples
DNA topoisomerase I (Topo I) is involved in DNA replication, transcription, recombination and repair...
Keywords: Gene expression, mRNA quantification, RT-PCR, topoisomerase I
07/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterQuantification of relative changes in specific mRNAs from frozen whole blood – methodological considerations and clinical implications
Keywords: frozen whole blood, Gene expression, globin mRNA, PAXgene®, Quality Control, sample size
02/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterHeat shock protein 70-1 gene expression in pediatric heart surgery using blood cardioplegia
Keywords: cardioplegia, congenital heart disease, Gene expression, heat shock proteins
02/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterImpaired synthesis of heme oxygenase-1 in Fanconi anemia cells can be rescued by transfection of Fanconi wild-type cDNA
Fanconi anemia is a fatal, hereditary chromosome instability syndrome of early childhood with progressive pancytopenia and cancer-proneness...
Keywords: antioxidative defense, BRCA1, Gene expression, reactive oxygen intermediates, thioredoxin, transcription
10/2008 | Biological Chemistry, Walter de GruyterThe histone H1 family: specific members, specific functions?
The linker histone H1 binds to the DNA entering and exiting the nucleosomal core particle and has an important role in establishing and maintaining higher order chromatin structures...
Keywords: chromatin, Gene expression, histone H1, variants
04/2008 | Biological Chemistry, Walter de GruyterNon-regulatory CD8+CD45RO+CD25+ T-lymphocytes may compensate for the loss of antigen-inexperienced CD8+CD45RA+ T-cells in old age
The age-related decline in immune system functions is responsible for the increased prevalence of infectious diseases and the low efficacy of vaccination in elderly individuals...
Keywords: aging, CD8 T-cell, Gene expression, Immune system, naive
05/2008 | Biological Chemistry, Walter de Gruyter