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Items for "GDF-5"

Monomeric and dimeric GDF-5 show equal type I receptor binding and oligomerization capability and have the same biological activity

Growth and differentiation factor 5 (GDF-5) is a homodimeric protein stabilized by a single disulfide bridge between cysteine 465 in the respective monomers, as well as by three intramolecular cysteine bridges within each subunit...

Keywords: BMP, BMP receptor, GDF-5, Smad signaling, TGF-? superfamily

04/2006 | Biological Chemistry, Walter de Gruyter