Depending on their interaction with intracellular proteins, G protein-coupled receptors (GPCR) often display different affinities for agonists at 37°C...
Keywords: G protein-coupled receptor, internalization, kinin, NPXXY
09/2004 | Biological Chemistry, Walter de GruyterA functional comparison was made between the wild-type bradykinin B2 receptor (B2wt) and the chimera B2eGFP (enhanced green-fluorescent protein fused to the C-terminus of B2wt), both stably expressed in HEK 293 cells...
Keywords: bradykinin B2 receptor, endocytosis, G protein-coupled receptor, green fluorescent protein
05/2006 | Biological Chemistry, Walter de Gruyter